RNA-based nanotechnology is an emerging field that harnesses RNA’s unique structural properties to create new nanostructures and machines. Perhaps more so than for other biomolecules, RNA tertiary structure is composed of discrete and recurring components known as tertiary ‘motifs’. Along with the helices that they interconnect, many of these structural motifs appear highly modular; that is, each motif folds into a well-defined three-dimensional (3D) structure in a broad range of contexts. By exploiting symmetry, motif repetition, expert modelling, and computational tools for visualization and modelling flexibility, these motifs have been assembled into new polyhedra, sheets, and cargo-carrying nanoparticles for biomedical use. Here you have an excellent example of this technology, where the scientists used a specific software for the computational design of custom RNA structures like this RNA tetraloop (PDB code: 6DVK)
#molecularart ... #immolecular ... #RNA ... #computerdesign ... #engineering ... #nanotechnology ... #tetraloop ... #xray
RNA tetraloop structure rendered with @proteinimaging and represented with @corelphotopaint
#molecularart ... #immolecular ... #RNA ... #computerdesign ... #engineering ... #nanotechnology ... #tetraloop ... #xray
RNA tetraloop structure rendered with @proteinimaging and represented with @corelphotopaint
