Paul C. Kuo, MD, has served as the Chair of the Department of Surgery at the University of South Florida since 2017 and is surgeon-in-chief at Tampa General Hospital. In addition to these roles, Paul C. Kuo, MD, has co-authored numerous scholarly articles about the role of osteopontin in different cancers.
Osteopontin is a protein found in the human bone matrix. The protein is crucial to the immune system for cell trafficking (the distribution of proteins and molecules throughout the cell) and bone remodeling (bone reshaping). It also contributes to processes in the immune system and vascular system such as immune response and tumorigenesis (the formation of tumors in the body).
Osteopontin affects tumor cell metastasis and the molecular activity within these sequences in various cancers including breast, brain, pancreatic, kidney, and other cancers. Osteopontin overexpression can prompt tumor metastasis by stimulating protein mediators in the body. Doctors have determined its potential impact on cancer therapy and the formation of new cancer treatments by studying osteopontin’s contribution to tumor developments.
Osteopontin is a protein found in the human bone matrix. The protein is crucial to the immune system for cell trafficking (the distribution of proteins and molecules throughout the cell) and bone remodeling (bone reshaping). It also contributes to processes in the immune system and vascular system such as immune response and tumorigenesis (the formation of tumors in the body).
Osteopontin affects tumor cell metastasis and the molecular activity within these sequences in various cancers including breast, brain, pancreatic, kidney, and other cancers. Osteopontin overexpression can prompt tumor metastasis by stimulating protein mediators in the body. Doctors have determined its potential impact on cancer therapy and the formation of new cancer treatments by studying osteopontin’s contribution to tumor developments.
